- Protects Against Common Cold

Acts against the cold virus

COLDGUARD™ is a unique product that fights against the cause of the common cold – cold virus. COLDGUARD™ is easy to use and works by forming a protective barrier on the mucous membrane of the mouth and throat, making it more difficult for the cold virus to cause illness. COLDGUARD™, used protectively, can help shorten the duration of a cold, by acting on the cold virus itself instead of just helping to relieve the symptoms.

COLDGUARD™ - Happy Family

A clinically proven product for the whole family

COLDGUARD™ is a CE-marked medical device.

COLDGUARD™ has a local, short-acting effect on the surface of the mucous membrane in your mouth and throat and can be used by adults and children age 4 and up. Over 3,5 million products have been used so far. Its performance and safety have been verified through clinical studies and customer surveys.¹


  • COLDGUARD Mouth Spray is a unique product that fights the cause of the common cold by forming a protective barrier against the common cold viruses. The COLDGUARD barrier consists of two ingredients that together provide the main effective result – Glycerol and Cod Trypsin.
    Traps: Glycerol creates an osmotically active barrier that traps viruses.
    Deactivates: Trypsin inhibits the viruses’ ability to bond, deactivating their ability to infect cells.
    Protects: The COLDGUARD™ barrier protects the oral cavity and throat.
    The COLDGUARD™ barrier protects the mouth and throat, helping the body to remove deactivated viruses in a natural way.
  • COLDGUARD™ is clinically documented that it can shorten the duration of illness if used protectively.²
  • COLDGUARD™ is used in the oral cavity and throat, where the cold virus takes hold and multiplies.
  • COLDGUARD™ is easy to use and begins working immediately by forming a protective barrier.
COLDGUARD™ How it works
ColdZyme® Munspray - Hur du använder

How to use COLDGUARD to help shorten the duration of a common cold

Start using COLDGUARD Mouth Spray as soon as possible after noticing symptoms of a common cold. Continue to use it until the symptoms are relieved.

  • Open your mouth and point the nozzle towards your throat.

  • Press the pump and spray 2 times (1 dose) every two hours up to 6 times a day.

How to Use COLDGUARD to prevent a common cold

If you do not have any symptoms of a common cold but are likely to be exposed to the common cold virus, for example when someone near you has a cold or if you are in a contagious environment such as a train or plane, or in an open plan office.

  • Open your mouth and point the nozzle towards your throat.

  • Press down the pump and spray 2 times (1 dose) every two hours up to 6 times daily while you are exposed to cold virus.

ColdZyme® Munspray - Upptäkten

Discovery of a protective enzyme from the Arctic Ocean

In the 1970s, Professor Jon Bragi Bjarnason, an Icelandic scientist, noticed that employees of a fish-cleaning plant had unusually soft and healthy hands. Considering that they cleaned fish all day, it seemed more logical for their hands to be full of cracks and cuts instead. Was there something in the fish that had a protective effect? The answer was yes. The research team was able to show that certain cold-adapted marine organisms contained an enzyme with good protective properties. Further research and development eventually led to a global patent on the marine enzyme – cod-adapted trypsin. The enzyme is extracted as a by-product of cod processing and thus does not put a load on the marine ecosystem.

The Swedish biotech company Enzymatica was founded in 2007 and acquired global rights to develop and sell products that contain the marine enzyme.

COLDGUARD reduces the viral load and cuts the number of illness days in half², when used prophylactically

COLDPREV is a double-blind, placebo-controlled study in which 46 healthy volunteers were infected with the cold virus (rhinovirus 16). Half of the participants were treated with COLDGUARD™ and half with placebo. The analysis and graph are based on the number of individuals who were confirmed to be infected by the virus or who exhibited cold symptoms. In the study, a statistically significant effect was seen for COLDGUARD™, i.e. a difference between COLDGUARD™ and placebo in relation to reduction of the cold viral load (-99 %) and reduction of the number of days of illness (-54 % or -3.5 days).

ColdZyme® Munspray - Förpackning

Product information

INGREDIENTS: Glycerol, water, cod trypsin, ethanol (<1 %), calcium chloride, trometamol and menthol. Contains no sugar or preservatives.

STORAGE: COLDGUARD™ should be stored at or below 25°C. Do not use after the expiry date printed on the product label and the pack.

Common cold

What is a cold?

The common cold is one of the most frequently occurring contagious illnesses. It is caused by a virus that enters the cells of the mucous membranes, primarily those of the nose, oral cavity and throat. Common symptoms include a runny or stuffy nose and sore throat. Symptoms may also include a mild cough and headache with fever. An ordinary cold usually lasts for fewer than ten days and, on average, people have two to four colds per year. Children are the group who catch colds most often – 5 to 10 colds per year – but this frequency declines with age.

Frequently asked questions about COLDGUARD™

COLDGUARD™ Mouth Spray


  • Do not use COLDGUARD™ if you are hypersensitive/allergic to any of the ingredients.
  • Do not inhale when applying the spray since it may cause transient asthma-like symptoms, such as coughing and hoarseness.
  • Consult a healthcare professional if you have a high fever or if your symptoms are more severe than those of a normal common cold; they could be due to something else.
  • Do not use the product for more than 30 consecutive days, as there is no clinical information about long-term use.
  • Keep out of reach of children, to prevent accidents with small parts.

For further information refer to COLDGUARD™ Mouth Spray instructions for use

Download the COLDGUARD™ Instructions for Use here for further information.

Contact Us

Tel: +27 (0)12 997 6974
Fax: +27 (0)86 618 9511
Medical / Regulatory / Technical Enquiries:

Find Us

Abex Pharmaceutica
Suite C, Rubenstein Ridge
617 Rubenstein Drive
Moreleta Park
South Africa


+27 (0)12 997 6974
for enquiries.

COLDGUARD is Available at Your Local Pharmacy
and Online at Dischem, Order Here

¹ Data on file
² M Clarsund et al, A Randomized, Double-Blind, Placebo-Controlled Pilot Clinical Study on ColdZyme® Mouth Spray against Rhinovirus-Induced Common Cold, Open Journal of Respiratory Diseases, 2017, 7, 125-135. (ColdGaurd is marketed as ColdZyme in the UK)